Medical Publications Archive

20 peer-reviewed studies, journals, and research papers — all source-linked.

20 results

PharmaceuticalSystematic Review

Ivermectin for Prevention and Treatment of COVID-19 Infection

Author: Bryant A et al.

Disease: COVID-19 / Viral Infections

Treatment: Ivermectin

Journal: American Journal of Therapeutics

Date: 2021-06-17

Meta-analysis of 24 RCTs: Ivermectin showed large, statistically significant reductions in COVID-19 mortality, hospitalization, and duration. WHO and FDA guidance actively contradicted this evidence. Drug is off-patent and costs under $1/dose.

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NutritionalProven

Vitamin D Supplementation and COVID-19 Risk

Author: Grant WB et al.

Disease: COVID-19 / Infectious Disease

Treatment: Vitamin D3 (High Dose)

Journal: Nutrients

Date: 2020-07-01

Virtually every severe COVID-19 patient was Vitamin D deficient. Evidence review shows Vitamin D upregulates innate immune antimicrobials, reduces cytokine storm risk, and modulates T-cell response. Governments promoted vaccines but not Vitamin D supplementation.

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AlternativeExperimental

Fenbendazole as a Potential Anticancer Drug

Author: Dogra N et al.

Disease: Cancer

Treatment: Fenbendazole

Journal: Scientific Reports

Date: 2019-01-15

Fenbendazole, an antiparasitic drug, showed complete tumor regression in animal models via microtubule disruption, GLUT transporter inhibition, and p53-mediated apoptosis. Human case series documented full remissions in stage 4 lung cancer.

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NutritionalClinical Trial

Ketogenic Diet and Alzheimer's Disease

Author: Croteau E et al.

Disease: Alzheimer's Disease

Treatment: Ketogenic / MCT Diet

Journal: Frontiers in Aging Neuroscience

Date: 2018-06-01

Ketone bodies provide alternative fuel for glucose-starved neurons in Alzheimer's brains. MCT oil supplementation documented significant cognitive improvements. Dr. Mary Newport documented dramatic reversal in her husband using coconut oil (MCT) — ignored by mainstream neurology.

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NutritionalProven

Primary Care-Led Weight Management for Remission of Type 2 Diabetes (DiRECT)

Author: Lean MEJ et al.

Disease: Type 2 Diabetes

Treatment: Very Low Calorie Diet

Journal: The Lancet

Date: 2018-02-10

46% of patients achieved full T2D remission at 1 year with no medications via calorie restriction. 86% of those who lost 15kg+ achieved remission. Demonstrates T2D is fully reversible through diet — rarely communicated to patients.

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NutritionalClinical Trial

Autoimmune Protocol Diet for Inflammatory Bowel Disease

Author: Konijeti GG et al.

Disease: Crohn's / IBD

Treatment: Autoimmune Protocol (AIP) Diet

Journal: Inflammatory Bowel Diseases

Date: 2017-11-01

78% of IBD patients achieved clinical remission after AIP elimination diet removing gluten, dairy, grains, legumes, nightshades. Endoscopic remission confirmed in 70%. Mechanism: removal of dietary antigens causing leaky gut and molecular mimicry.

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NutritionalClinical Trial

Aged Garlic Extract Reduces Arterial Plaque: A Randomized Controlled Trial

Author: Budoff MJ et al.

Disease: Cardiovascular Disease

Treatment: Aged Garlic Extract

Journal: Journal of the American College of Cardiology

Date: 2016-10-25

Double-blind RCT: Aged Garlic Extract reduced low-attenuation plaque volume by 4.7% compared to progression in placebo group. Also reduced coronary artery calcium progression. Costs ~$20/month with no adverse events.

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AlternativeClinical Trial

Reversal of Cognitive Decline: A Novel Therapeutic Program

Author: Bredesen DE

Disease: Alzheimer's Disease

Treatment: ReCODE Protocol (Bredesen)

Journal: Aging

Date: 2014-09-27

9 out of 10 patients with Alzheimer's and MCI showed measurable cognitive reversal using a personalized metabolic protocol targeting 36 factors (diet, sleep, exercise, toxins, hormones, nutrients). No pharmaceutical drugs used.

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NutritionalProven

Fasting: Molecular Mechanisms and Clinical Applications

Author: Longo VD, Mattson MP

Disease: Multiple Metabolic Diseases

Treatment: Intermittent Fasting

Journal: Cell Metabolism

Date: 2014-02-04

Fasting triggers autophagy (Nobel Prize 2016 - Ohsumi), reduces insulin resistance, improves mitochondrial function, reduces inflammation, and reverses metabolic syndrome. Pharmaceutical industry cannot patent or profit from fasting.

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NutritionalProven

Magnesium Deficiency and Cardiovascular Disease

Author: Del Gobbo LC et al.

Disease: Cardiovascular Disease

Treatment: Magnesium Supplementation

Journal: American Journal of Clinical Nutrition

Date: 2013-01-01

Meta-analysis: magnesium deficiency directly causes arrhythmia, hypertension, and arterial calcification. Most modern populations are deficient due to soil depletion. Supplementation costs ~$5/month. Rarely prescribed despite overwhelming mechanistic and epidemiological evidence.

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HerbalClinical Trial

Lion's Mane Mushroom and Mild Cognitive Impairment

Author: Mori K et al.

Disease: Alzheimer's / Cognitive Decline

Treatment: Lion's Mane Mushroom

Journal: Phytotherapy Research

Date: 2009-03-23

Double-blind RCT: Lion's Mane (Hericium erinaceus) showed significant cognitive improvement in adults with mild cognitive impairment at 16 weeks. Effect reversed after discontinuation, confirming direct causality. Mechanism: NGF (Nerve Growth Factor) stimulation.

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HerbalProven

St. John's Wort for Major Depression

Author: Linde K et al.

Disease: Depression

Treatment: St. John's Wort (Hypericum)

Journal: Cochrane Database of Systematic Reviews

Date: 2008-10-08

Meta-analysis of 29 trials (5,489 patients): St. John's Wort superior to placebo and similarly effective as standard antidepressants for mild-moderate depression, with significantly fewer side effects and discontinuations.

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HerbalExperimental

Curcumin and Cancer: An Old-Age Disease with an Age-Old Solution

Author: Kunnumakkara AB et al.

Disease: Multiple Cancers

Treatment: Curcumin

Journal: Cancer Letters

Date: 2008-07-01

Curcumin inhibits NF-κB, induces apoptosis, suppresses angiogenesis, and blocks tumor invasion across 30+ cancer types in vitro and in vivo. No significant toxicity at therapeutic doses.

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HerbalClinical Trial

Berberine and Its Study on Type 2 Diabetes

Author: Zhang Y et al.

Disease: Type 2 Diabetes

Treatment: Berberine

Journal: Metabolism

Date: 2008-05-01

Head-to-head RCT: Berberine matched Metformin in HbA1c reduction (2.0% vs 2.0%), fasting glucose, and postprandial glucose. Berberine also reduced triglycerides and LDL significantly more than Metformin with fewer GI side effects.

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PharmaceuticalProven

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data

Author: Kirsch I et al.

Disease: Depression

Treatment: SSRIs (Reanalysis)

Journal: PLOS Medicine

Date: 2008-02-26

Reanalysis of all FDA-submitted SSRI trial data including unpublished trials: true drug-placebo difference is below clinical significance for all but severely depressed patients. SSRI effect is largely placebo. True NNT estimated at 16–30.

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Physical TherapyProven

Exercise and Pharmacotherapy in the Treatment of Major Depressive Disorder

Author: Blumenthal JA et al.

Disease: Depression

Treatment: Aerobic Exercise

Journal: Psychosomatic Medicine

Date: 2007-09-01

Duke SMILE Trial follow-up: exercise equivalent to Sertraline for major depression at 16 weeks. Exercise group had significantly lower relapse rates at 10-month follow-up. No side effects, no cost after initial period.

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NutritionalClinical Trial

Intravenously Administered Vitamin C as Cancer Therapy

Author: Padayatty SJ et al.

Disease: Cancer

Treatment: High-Dose IV Vitamin C

Journal: CMAJ

Date: 2006-03-28

NIH-confirmed pro-oxidant mechanism: at high plasma concentrations, Vitamin C generates hydrogen peroxide selectively toxic to cancer cells while sparing normal cells. Three documented cases of unexpected cancer remission.

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ChemotherapyProven

Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies

Author: Morgan G, Ward R, Barton M

Disease: All Cancers

Treatment: Chemotherapy (Meta-Analysis)

Journal: Clinical Oncology

Date: 2004-12-01

Systematic analysis of all randomized trials in Australia and USA: chemotherapy contributes only 2.1% to 5-year survival across all adult cancers combined. Authors call for honest disclosure to patients about marginal benefit.

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NutritionalProven

Dietary Approaches to Stop Hypertension (DASH)

Author: Appel LJ et al.

Disease: Hypertension

Treatment: DASH Diet

Journal: New England Journal of Medicine

Date: 1997-04-17

DASH diet reduced systolic BP by 8–14 mmHg — equivalent to first-line antihypertensive drug therapy — with no medications, no side effects, and additional benefits for cholesterol and metabolic health.

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NutritionalClinical Trial

Reversal of Coronary Artery Disease: A 5-Year Clinical Follow-Up Study

Author: Esselstyn CB Jr

Disease: Cardiovascular Disease

Treatment: Whole-Food Plant-Based Diet

Journal: Journal of Family Practice

Date: 1995-08-01

12-year follow-up: zero cardiac events in fully compliant patients on whole-food plant-based diet. Documented angiographic reversal of coronary artery disease. Zero pharmaceutical intervention. Cardiology industry has no financial incentive to promote.

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